instruction
stringlengths 30
82
| output
stringlengths 13
790
|
|---|---|
Which methods support the evidence found for the RS1593446655 SNP? | Associated methods are: clinical testing. |
What is the clinical significance of RS1593446655 SNP, is it benign or pathogenic? | It is Likely benign. |
How long is the variation length for RS1593446655 SNP? | The variation length is 1 base pairs. |
What is the origin for RS1593446655 SNP? | The origin is germline. |
What is the type of genetic variation for RS1593446655 SNP? | The variation is a single nucleotide variant. |
What is the genetic molecular consequence for RS1593446655 SNP? | The resulting gene consequence is a synonymous variant. |
Which condition is asociated with RS1593532014 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593532014 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593532014 SNP. |
In which chromosome is RS1593532014 SNP located? | It is located in the chromosome 13. |
Which methods support the evidence found for the RS1593532014 SNP? | Associated methods are: clinical testing. |
What is the clinical significance of RS1593532014 SNP, is it benign or pathogenic? | It is Likely benign. |
How long is the variation length for RS1593532014 SNP? | The variation length is 1 base pairs. |
What is the origin for RS1593532014 SNP? | The origin is germline. |
What is the type of genetic variation for RS1593532014 SNP? | The variation is a single nucleotide variant. |
What is the genetic molecular consequence for RS1593532014 SNP? | The resulting gene consequence is a synonymous variant. |
Which condition is asociated with RS1593434283 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593434283 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593434283 SNP. |
In which chromosome is RS1593434283 SNP located? | It is located in the chromosome 13. |
Which methods support the evidence found for the RS1593434283 SNP? | Associated methods are: clinical testing. |
What is the clinical significance of RS1593434283 SNP, is it benign or pathogenic? | It is Likely benign. |
How long is the variation length for RS1593434283 SNP? | The variation length is 1 base pairs. |
What is the origin for RS1593434283 SNP? | The origin is germline. |
What is the type of genetic variation for RS1593434283 SNP? | The variation is a single nucleotide variant. |
What is the genetic molecular consequence for RS1593434283 SNP? | The resulting gene consequence is a synonymous variant. |
Which condition is asociated with RS1060504827 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1060504827 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1060504827 SNP. |
In which chromosome is RS1060504827 SNP located? | It is located in the chromosome 13. |
Which methods support the evidence found for the RS1060504827 SNP? | Associated methods are: clinical testing. |
What is the clinical significance of RS1060504827 SNP, is it benign or pathogenic? | It is Likely benign. |
How long is the variation length for RS1060504827 SNP? | The variation length is 1 base pairs. |
What is the origin for RS1060504827 SNP? | The origin is germline. |
What is the type of genetic variation for RS1060504827 SNP? | The variation is a single nucleotide variant. |
What is the genetic molecular consequence for RS1060504827 SNP? | The resulting gene consequence is a synonymous variant. |
Which condition is asociated with RS1021965284 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1021965284 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1021965284 SNP. |
In which chromosome is RS1021965284 SNP located? | It is located in the chromosome 13. |
Which methods support the evidence found for the RS1021965284 SNP? | Associated methods are: clinical testing. |
What is the clinical significance of RS1021965284 SNP, is it benign or pathogenic? | It is Likely benign. |
How long is the variation length for RS1021965284 SNP? | The variation length is 1 base pairs. |
What is the origin for RS1021965284 SNP? | The origin is germline. |
What is the type of genetic variation for RS1021965284 SNP? | The variation is a single nucleotide variant. |
What is the genetic molecular consequence for RS1021965284 SNP? | The resulting gene consequence is a synonymous variant. |
Which condition is asociated with RS3092886 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS3092886 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS3092886 SNP. |
In which chromosome is RS3092886 SNP located? | It is located in the chromosome 13. |
Which methods support the evidence found for the RS3092886 SNP? | Associated methods are: clinical testing. |
What is the clinical significance of RS3092886 SNP, is it benign or pathogenic? | It is Benign. |
How long is the variation length for RS3092886 SNP? | The variation length is 1 base pairs. |
What is the origin for RS3092886 SNP? | The origin is germline. |
What is the type of genetic variation for RS3092886 SNP? | The variation is a single nucleotide variant. |
What is the genetic molecular consequence for RS3092886 SNP? | The resulting gene consequence is a intron variant. |
Which condition is asociated with RS1593455621 SNP? | Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS1593455621 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS1593455621 SNP. |
In which chromosome is RS1593455621 SNP located? | It is located in the chromosome 13. |
Which methods support the evidence found for the RS1593455621 SNP? | Associated methods are: clinical testing. |
What is the clinical significance of RS1593455621 SNP, is it benign or pathogenic? | It is Pathogenic. |
How long is the variation length for RS1593455621 SNP? | The variation length is 1 base pairs. |
What is the origin for RS1593455621 SNP? | The origin is unknown. |
What is the type of genetic variation for RS1593455621 SNP? | The variation is a single nucleotide variant. |
What is the genetic molecular consequence for RS1593455621 SNP? | The resulting gene consequence is a nonsense. |